The genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer
Published on:
Sydney Cancer Partners Director, Professor Anna DeFazio, her team at Westmead and collaborators from the PeterMac, and other international research groups have a new publication in Nature Genetics. research was recently published in Nature Genetics. Read about the research results from a study analysing 60 patients with advanced-stage HGSC who survived more than 10 years after diagnosis using whole-genome sequencing, transcriptome and methylome profiling of their primary tumor samples, comparing this data to 66 short-or moderate-term survivors.
Fewer than half of all patients with advanced-stage high-grade serous
ovarian cancers (HGSCs) survive more than five years after diagnosis, but
those who have an exceptionally long survival could provide insights into
tumor biology and therapeutic approaches.
Read full publication.